HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: ZN490 (Q9ULM2)
Zinc finger protein 490
Gene: ZNF490

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24623722
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 529
+	Hs
		359630 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF20_HUMAN (55-529): 4.77e-159: 464: 55.58
+	Hs
		360176 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN439_HUMAN (55-527): 3.26e-150: 441: 51.89
+	Hs
		360195 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN564_HUMAN (97-404): 1.66e-118: 362: 43.73
+	Hs
		443312 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ZNF20_HUMAN (55-529): 4.77e-159: 464: 55.58
+	Hs
		535321 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		ZNF20_HUMAN (55-529): 4.77e-159: 464: 55.58
+	Hs
		360508 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZNF69_HUMAN (133-394): 1.88e-69: 234: 50.00
+	Hs
		359941 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN345_HUMAN (318-529): 3.13e-59: 205: 52.83
+	Hs
		360134 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN440_HUMAN (133-338): 1.9e-47: 176: 44.78
+	Hs
		360017 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN569_HUMAN (89-217): 1.23e-35: 143: 35.39
+	Hs
		67847 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		ZN724_HUMAN (89-155): 5.19e-13: 73.6: 22.06
+	Hs
		443282 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ZN888_HUMAN (90-244): 7.22e-46: 172: 32.69
+	Hs
		422202 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ZNF57_HUMAN (133-351): 6.78e-47: 173: 43.88