HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25948554, 16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 2752
+	Hs
		595471 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		443883 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		359745 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		360312 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		975718 LMNB2_HUMAN (21-580): 7.45e-51: 188: 52.68		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1205250 K2C73_HUMAN (23-390): 1.74e-50: 185: 23.85		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		595369 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		443385 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		MAP1B_HUMAN (15-1517): 8.71e-69: 261: 10.13
+	Hs
		443743 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		360224 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		360045 LMNA_HUMAN (1-664): 7.64e-79: 265: 100.00		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Dr
		71432 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		NIPLB_DANRE (1227-2064): 1.18e-23: 112: 15.43
+	Hs
		595271 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		443800 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		TARA_HUMAN (1540-2752): 1.5e-31: 138: 11.50
+	Hs
		443464 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		422166 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23