Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: ANK1 (P16157)
Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)
Gene: ANK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 15929114, 2971657
Identification Methods enzymatic study, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, Spectrin~UPA_2, Spectrin~ZU5
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0009898 - cytoplasmic side of plasma membrane
GO:0014731 - spectrin-associated cytoskeleton
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024