HitPredict

Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2419 Hs			1 245
+	Hs
		297821 K0754_HUMAN (1-1619): 1.14e-89: 330: 14.06		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		297824 K0754_HUMAN (1-1619): 1.14e-89: 330: 14.06		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		297815 K0754_HUMAN (1-1619): 1.14e-89: 330: 14.06		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		683277 CENPE_HUMAN (626-2397): 1.4e-57: 224: 10.42		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		646909 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927068 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		646893 GOGB1_HUMAN (818-2397): 1.05e-41: 172: 9.47		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		909544 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Mm
		926889 PLEC_MOUSE (1-1297): 6.53e-40: 166: 10.27		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		927025 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Mm
		82753 B9EKJ1_MOUSE (2-1574): 1.12e-37: 158: 15.92		1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00
+	Hs
		506805 SPTB1_HUMAN (1158-2357): 1.16e-37: 158: 17.37		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		683333 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Mm
		82777 B9EKJ1_MOUSE (2-1574): 1.12e-37: 158: 15.92		1433B_MOUSE (1-242): 2.84e-124: 354: 80.99
+	Hs
		521518 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684048 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982032 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		684024 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		981996 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904543 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33