HitPredict

Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	16889989
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2419 Hs			1 1312
+	Hs
		521484 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Dm
		404218 ACTN_DROME (1898-2418): 3.04e-51: 200: 26.27		MYSA_DROME (74-929): 3.37e-23: 109: 13.56
+	Hs
		724839 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		724817 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		1068548 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Hs
		522612 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		MYH7_HUMAN (524-1249): 1.05e-24: 114: 10.81
+	Hs
		1068617 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		724994 CP250_HUMAN (4-1123): 1.7e-36: 154: 10.47		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		148339 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		1045471 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		1113839 CP250_HUMAN (4-1123): 1.7e-36: 154: 10.47		GRDN_HUMAN (530-1217): 5.01e-21: 102: 12.32
+	Mm
		1149152 CE290_MOUSE (747-2384): 1.71e-34: 148: 9.54		SMC1A_MOUSE (290-1274): 4e-19: 96.1: 11.16
+	Hs
		148841 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Mm
		93578 PLEC_MOUSE (1-1297): 6.53e-40: 166: 10.27		DESP_MOUSE (190-1069): 1.15e-11: 72: 18.72
+	Hs
		164575 SPTN2_HUMAN (1474-2371): 7.55e-25: 116: 16.03		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		148786 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		148330 SPTB1_HUMAN (1158-2357): 1.16e-37: 158: 17.37		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		149277 SPTN4_HUMAN (4-762): 6.94e-37: 156: 19.50		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		164647 SPTN2_HUMAN (1474-2371): 7.55e-25: 116: 16.03		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		148142 SPTN2_HUMAN (1474-2371): 7.55e-25: 116: 16.03		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15