HitPredict

Interactor 1: A0A142JA41 (A0A142JA41)
HLA-C alpha chain for Cw*18GB (MHC class I antigen)
Gene: HLA-C

Interactor 2: KI2L1 (P43626)
Killer cell immunoglobulin-like receptor 2DL1 (CD158 antigen-like family member A) (Natural killer-associated transcript 1) (NKAT-1) (p58 natural killer cell receptor clones CL-42/47.11) (p58 NK receptor CL-42/47.11) (p58.1 MHC class-I-specific NK receptor) (CD antigen CD158a)
Gene: KIR2DL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	18322206
Identification Methods	affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 366 Hs			1 348
+	Hs
		798173 Q5RIP0_HUMAN (1-366): 1.07e-171: 484: 96.18		KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54
+	Hs
		798195 Q5S3G3_HUMAN (1-365): 3.81e-177: 498: 83.29		KI2L3_HUMAN (1-340): 3.49e-131: 379: 90.32
+	Hs
		798171 Q5D1W8_HUMAN (1-366): 1.25e-170: 481: 97.27		KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54
+	Hs
		798148 Q5RIP0_HUMAN (1-366): 1.07e-171: 484: 96.18		KI2L1_HUMAN (1-348): 1.19e-135: 391: 100.00
+	Hs
		798146 Q5D1W8_HUMAN (1-366): 1.25e-170: 481: 97.27		KI2L1_HUMAN (1-348): 1.19e-135: 391: 100.00
+	Hs
		798194 Q5RIP0_HUMAN (1-366): 1.07e-171: 484: 96.18		KI2L3_HUMAN (1-340): 3.49e-131: 379: 90.32
+	Hs
		798280 Q5S3G3_HUMAN (1-365): 3.81e-177: 498: 83.29		KI2S4_HUMAN (1-303): 3.14e-122: 355: 87.83
+	Hs
		382484 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		LIRB4_HUMAN (1-324): 5.2e-81: 255: 29.46
+	Hs
		1060406 Q95J06_HUMAN (1-365): 0: 511: 81.92		KI3S1_HUMAN (1-348): 2.28e-64: 210: 30.48
+	Hs
		382420 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		KI3S1_HUMAN (1-348): 2.28e-64: 210: 30.48
+	Hs
		47499 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		A0A8I5QEB2_HUMAN (1-246): 4.55e-64: 210: 40.56
+	Hs
		1060403 Q5SUL5_HUMAN (1-365): 5.72e-175: 492: 81.92		KI3S1_HUMAN (1-348): 2.28e-64: 210: 30.48
+	Hs
		382341 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		KI3L2_HUMAN (1-348): 2.38e-60: 202: 31.62
+	Hs
		798244 Q5S3G3_HUMAN (1-365): 3.81e-177: 498: 83.29		KI3L2_HUMAN (1-348): 2.38e-60: 202: 31.62
+	Hs
		1245576 Q95J06_HUMAN (1-365): 0: 511: 81.92		LIRB1_HUMAN (12-122): 6.45e-17: 83.7: 35.14
+	Hs
		1232786 Q95J06_HUMAN (1-365): 0: 511: 81.92		LIRB2_HUMAN (10-138): 1.23e-15: 79.9: 35.66
+	Hs
		382485 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		LIRB1_HUMAN (12-122): 6.45e-17: 83.7: 35.14
+	Hs
		1130838 Q5S3G3_HUMAN (1-365): 3.81e-177: 498: 83.29		LIRB1_HUMAN (12-122): 6.45e-17: 83.7: 35.14
+	Hs
		382478 HLAA_HUMAN (1-365): 6.83e-178: 500: 83.01		LIRB2_HUMAN (10-138): 1.23e-15: 79.9: 35.66
+	Hs
		1130837 Q5S3G3_HUMAN (1-365): 3.81e-177: 498: 83.29		LIRB2_HUMAN (10-138): 1.23e-15: 79.9: 35.66