HitPredict

Interactor 1: TBB (P02557)
Tubulin beta chain (Beta-tubulin)
Gene: TUB2

Interactor 2: SMC5 (Q08204)
Structural maintenance of chromosomes protein 5
Gene: SMC5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	25135640
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 457 Sc			1 1093
+	Hs
		1037287 TBB3_HUMAN (1-444): 0: 709: 75.00		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		428293 TBB5_HUMAN (1-429): 0: 708: 76.92		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		933883 TBB4B_HUMAN (1-427): 0: 707: 77.05		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		1221696 TBB2B_HUMAN (1-430): 0: 706: 76.51		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		1046506 TBB2A_HUMAN (1-430): 0: 703: 76.28		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		381238 TBB4A_HUMAN (1-427): 0: 702: 77.28		SMC5_HUMAN (16-1076): 2.66e-85: 301: 23.96
+	Hs
		428501 TBB5_HUMAN (1-429): 0: 708: 76.92		SMC3_HUMAN (40-986): 3.81e-46: 183: 12.10
+	Sc
		361101 TBB_YEAST (1-457): 0: 705: 100.00		SMC6_YEAST (34-1052): 8.61e-47: 184: 12.17
+	Hs
		1037412 TBB3_HUMAN (1-444): 0: 709: 75.00		SMC4_HUMAN (87-1067): 1.34e-41: 168: 9.15
+	Sc
		361083 TBB_YEAST (1-457): 0: 705: 100.00		SMC4_YEAST (197-1048): 2.8e-38: 158: 11.60
+	Hs
		311538 TBB3_HUMAN (1-444): 0: 709: 75.00		SMC2_HUMAN (150-1050): 5.68e-32: 137: 10.22
+	Hs
		933814 TBB4B_HUMAN (1-427): 0: 707: 77.05		SMC1A_HUMAN (162-1050): 5.4e-31: 134: 10.29
+	Sc
		360877 TBB_YEAST (1-457): 0: 705: 100.00		SMC2_YEAST (140-1050): 2.94e-30: 131: 10.35