HitPredict

Interactor 1: MYO4 (P02566)
Myosin-4 (Myosin heavy chain B) (MHC B) (Uncoordinated protein 54)
Gene: unc-54

Interactor 2: MLE (P53014)
Myosin, essential light chain (Myosin light chain alkali)
Gene: mlc-3

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_8~Myosin_head
Common GO terms	GO:0005859 - muscle myosin complex GO:0005863 - striated muscle myosin thick filament
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1963 Ce			1 153
+	Ce
		522310 MYO3_CAEEL (937-1962): 6.59e-62: 237: 17.38		MLE_CAEEL (1-153): 2.42e-62: 190: 100.00
+	Hs
		441665 MYH9_HUMAN (1081-1961): 3.71e-55: 215: 14.79		MYL3_HUMAN (3-146): 1.3e-61: 189: 44.22
+	Ce
		361125 MYO1_CAEEL (1016-1952): 5.01e-51: 201: 15.41		MLE_CAEEL (1-153): 2.42e-62: 190: 100.00
+	Hs
		441674 MYH14_HUMAN (1010-1948): 1.88e-49: 196: 14.70		MYL3_HUMAN (3-146): 1.3e-61: 189: 44.22
+	Hs
		724737 MYH9_HUMAN (1081-1961): 3.71e-55: 215: 14.79		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Hs
		409452 MYH10_HUMAN (733-1643): 6.37e-41: 168: 14.90		MYL1_HUMAN (1-146): 5.13e-63: 193: 43.54
+	Ce
		522317 MYO2_CAEEL (1140-1962): 1.52e-41: 171: 16.07		MLE_CAEEL (1-153): 2.42e-62: 190: 100.00
+	Hs
		648467 MYH9_HUMAN (1081-1961): 3.71e-55: 215: 14.79		CALL3_HUMAN (1-146): 2.7e-45: 146: 34.01
+	Hs
		538642 MYH9_HUMAN (1081-1961): 3.71e-55: 215: 14.79		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	Hs
		441666 MYH10_HUMAN (733-1643): 6.37e-41: 168: 14.90		MYL3_HUMAN (3-146): 1.3e-61: 189: 44.22
+	Hs
		891551 MYH14_HUMAN (1010-1948): 1.88e-49: 196: 14.70		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Hs
		538680 MYH14_HUMAN (1010-1948): 1.88e-49: 196: 14.70		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	Hs
		725124 MYH10_HUMAN (733-1643): 6.37e-41: 168: 14.90		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Dm
		404214 MYSA_DROME (950-1951): 2.26e-56: 219: 16.99		MLC1_DROME (24-148): 1.04e-27: 102: 44.53
+	Hs
		538643 MYH10_HUMAN (733-1643): 6.37e-41: 168: 14.90		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	Gg
		361265 MYH11_CHICK (1665-1963): 2.82e-17: 91.3: 17.33		MYL6_CHICK (1-147): 7.35e-50: 158: 42.57
+	Hs
		728458 MYH11_HUMAN (1638-1959): 6.21e-15: 83.6: 16.56		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Dm
		870145 MYSN_DROME (1496-1963): 2.42e-22: 107: 14.93		MLC2_DROME (1-147): 5.8e-32: 112: 42.67