HitPredict

Interactor 1: ACT4 (P02574)
Actin, larval muscle (EC 3.6.4.-) (Actin-79B)
Gene: Act79B

Interactor 2: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29249285
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Dm			1 2415
+	Dm
		501483 ACT1_DROME (1-376): 0: 601: 95.75		SPTCA_DROME (1-2415): 0: 624: 100.00
+	Dm
		501441 ACT5_DROME (1-376): 0: 600: 96.81		SPTCA_DROME (1-2415): 0: 624: 100.00
+	Dm
		361136 ACT2_DROME (1-376): 0: 599: 95.21		SPTCA_DROME (1-2415): 0: 624: 100.00
+	Dm
		527089 ACT3_DROME (1-376): 0: 598: 96.54		SPTCA_DROME (1-2415): 0: 624: 100.00
+	Dm
		527091 ACT6_DROME (1-376): 0: 597: 97.07		SPTCA_DROME (1-2415): 0: 624: 100.00
+	Hs
		891755 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98
+	Hs
		929856 ACTG_HUMAN (3-376): 0: 597: 94.65		SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98
+	Hs
		932975 ACTS_HUMAN (2-376): 0: 592: 91.47		SPTN1_HUMAN (10-2415): 1.94e-179: 613: 63.98
+	Hs
		164588 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTN2_HUMAN (115-1879): 1.3e-66: 253: 18.92
+	Hs
		506816 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTB1_HUMAN (5-1573): 1.71e-64: 246: 19.76
+	Hs
		891697 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTB2_HUMAN (1135-2380): 1.09e-32: 142: 17.57
+	Hs
		929824 ACTG_HUMAN (3-376): 0: 597: 94.65		SPTB2_HUMAN (1135-2380): 1.09e-32: 142: 17.57
+	Hs
		892003 ACTB_HUMAN (1-376): 0: 598: 94.15		CP250_HUMAN (1-878): 4.53e-26: 120: 7.95
+	Hs
		891706 ACTB_HUMAN (1-376): 0: 598: 94.15		DYST_HUMAN (720-2406): 4.42e-25: 117: 8.74
+	Dm
		361167 ACT4_DROME (1-376): 0: 593: 100.00		ACTN_DROME (678-1113): 9.69e-19: 95.9: 14.44
+	Hs
		211548 ACTB_HUMAN (1-376): 0: 598: 94.15		ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87
+	Hs
		211561 ACTS_HUMAN (2-376): 0: 592: 91.47		ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87
+	Hs
		725637 ACTB_HUMAN (1-376): 0: 598: 94.15		ACTN2_HUMAN (1983-2260): 1.82e-09: 65.5: 23.63
+	Hs
		892113 ACTB_HUMAN (1-376): 0: 598: 94.15		MACF1_HUMAN (870-2382): 4.99e-09: 64.3: 7.81
+	Hs
		360636 ACTS_HUMAN (2-376): 0: 592: 91.47		SPTA1_HUMAN (5-502): 5.94e-10: 67.4: 20.62