HitPredict

Interactor 1: ACT4 (P02574)
Actin, larval muscle (EC 3.6.4.-) (Actin-79B)
Gene: Act79B

Interactor 2: ACTN (P18091)
Alpha-actinin, sarcomeric (F-actin cross-linking protein)
Gene: ACTN

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 376 Dm			1 924
+	Hs
		211548 ACTB_HUMAN (1-376): 0: 598: 94.15		ACTN4_HUMAN (14-924): 0: 598: 67.40
+	Hs
		725637 ACTB_HUMAN (1-376): 0: 598: 94.15		ACTN2_HUMAN (5-924): 0: 595: 66.41
+	Hs
		211560 ACTC_HUMAN (2-376): 0: 592: 92.53		ACTN4_HUMAN (14-924): 0: 598: 67.40
+	Hs
		211561 ACTS_HUMAN (2-376): 0: 592: 91.47		ACTN4_HUMAN (14-924): 0: 598: 67.40
+	Oc
		933099 ACTS_RABIT (2-376): 0: 592: 91.47		Q07931_RABIT (21-276): 5.3e-96: 305: 80.47
+	Hs
		891755 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTN1_HUMAN (307-729): 7.36e-14: 78.6: 16.16
+	Hs
		929856 ACTG_HUMAN (3-376): 0: 597: 94.65		SPTN1_HUMAN (307-729): 7.36e-14: 78.6: 16.16
+	Hs
		506816 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTB1_HUMAN (199-857): 8.97e-13: 75: 10.56
+	Hs
		891697 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTB2_HUMAN (229-834): 7.9e-13: 75: 11.18
+	Hs
		929824 ACTG_HUMAN (3-376): 0: 597: 94.65		SPTB2_HUMAN (229-834): 7.9e-13: 75: 11.18
+	Hs
		932145 ACTC_HUMAN (2-376): 0: 592: 92.53		SPTN1_HUMAN (307-729): 7.36e-14: 78.6: 16.16
+	Hs
		932975 ACTS_HUMAN (2-376): 0: 592: 91.47		SPTN1_HUMAN (307-729): 7.36e-14: 78.6: 16.16
+	Hs
		932107 ACTC_HUMAN (2-376): 0: 592: 92.53		SPTB2_HUMAN (229-834): 7.9e-13: 75: 11.18
+	Dm
		284844 ACT1_DROME (1-376): 0: 601: 95.75		O77291_DROME (223-823): 3.09e-09: 63.5: 11.49
+	Hs
		164588 ACTB_HUMAN (1-376): 0: 598: 94.15		SPTN2_HUMAN (197-778): 5.17e-09: 62.7: 11.98