HitPredict

Interactor 1: S10A1 (P02639)
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)
Gene: S100A1

Interactor 2: FKBP4 (Q9TRY0)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (FK506-binding protein 4) (FKBP-4) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	14638689
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 94 Bt			1 459
+	Hs
		615212 S10A1_HUMAN (1-94): 5.7e-38: 123: 98.94		FKBP4_HUMAN (1-459): 1.72e-145: 425: 88.67
+	Hs
		661236 S10A2_HUMAN (1-90): 8.74e-32: 108: 52.22		FKBP4_HUMAN (1-459): 1.72e-145: 425: 88.67
+	Hs
		416611 S10A6_HUMAN (1-90): 8.82e-27: 95.7: 43.33		FKBP4_HUMAN (1-459): 1.72e-145: 425: 88.67
+	Mm
		534549 S10A6_MOUSE (1-88): 8.09e-26: 93: 45.46		FKBP4_MOUSE (1-459): 9.62e-144: 420: 88.24
+	Bt
		361270 S10A1_BOVIN (1-94): 5.16e-38: 124: 100.00		PPID_BOVIN (110-416): 1.06e-50: 177: 21.53
+	Hs
		615214 S10A1_HUMAN (1-94): 5.7e-38: 123: 98.94		PPID_HUMAN (132-416): 5.67e-49: 173: 21.45
+	Hs
		661244 S10A2_HUMAN (1-90): 8.74e-32: 108: 52.22		PPID_HUMAN (132-416): 5.67e-49: 173: 21.45
+	Hs
		416614 S10A6_HUMAN (1-90): 8.82e-27: 95.7: 43.33		PPID_HUMAN (132-416): 5.67e-49: 173: 21.45
+	Hs
		416354 S10A9_HUMAN (3-92): 1.73e-29: 102: 37.36		FKBP2_HUMAN (134-257): 1.07e-19: 87.2: 20.00