Interactor 1: APOA1 (P02647)
Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))]
Gene: APOA1

Interactor 2: APOA1 (P02647)
Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))]
Gene: APOA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 8810909, 9356442, 15174051, 11744719, 17676061, 18719128, 20133843, 20884842, 22184756, 22609356, 24316228, 24702826
Identification Methods pull down, x-ray crystallography, affinity chromatography technology, protein cross-linking with a bifunctional reagent, cross-linking study, light microscopy, classical fluorescence spectroscopy, cosedimentation in solution, x-ray fiber diffraction, transmission electron microscopy and 5 others

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Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Apolipoprotein~Apolipoprotein
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001932 - regulation of protein phosphorylation
GO:0001935 - endothelial cell proliferation
GO:0002719 - negative regulation of cytokine production involved in immune response
GO:0005102 - signaling receptor binding
and 76 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 267
Hs

1 267
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024