HitPredict

Interactor 1: APOA1 (P02647)
Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))]
Gene: APOA1

Interactor 2: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 18263896
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0062023 - collagen-containing extracellular matrix and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 267 Hs			1 250
+	Hs
		121069 APOA1_HUMAN (1-267): 1.25e-86: 260: 100.00		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		361432 APOE_HUMAN (1-267): 1.21e-53: 178: 20.82		LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00
+	Hs
		119067 APOE_HUMAN (1-267): 1.21e-53: 178: 20.82		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67