Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 21163940, 15182176
Identification Methods two hybrid, pull down, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Apolipoprotein~Apolipoprotein
Common GO terms GO:0000302 - response to reactive oxygen species
GO:0001540 - amyloid-beta binding
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0002021 - response to dietary excess
GO:0005102 - signaling receptor binding
and 143 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 317
Hs

1 317
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024