Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: LCAT (P04180)
Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43) (1-alkyl-2-acetylglycerophosphocholine esterase) (EC 3.1.1.47) (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase) (Platelet-activating factor acetylhydrolase) (PAF acetylhydrolase)
Gene: LCAT

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 15654758
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0008203 - cholesterol metabolic process
GO:0034364 - high-density lipoprotein particle
GO:0034372 - very-low-density lipoprotein particle remodeling
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 317
Hs

1 440
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024