Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.714

The method score is based on:

Property Details
Experiments 8620924, 32812023, 7566652, 26402096, 32814053
Identification Methods pull down, affinity chromatography technology, unspecified method, anti bait coimmunoprecipitation, validated two hybrid, electrophoretic mobility-based method, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0010629 - negative regulation of gene expression
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 317
Hs

1 758
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024