Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: PSN1 (P49768)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: PSEN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.55 0.518

The method score is based on:

Property Details
Experiments 21163940
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0010629 - negative regulation of gene expression
and 9 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024