HitPredict

Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: LRP8 (Q14114)
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
Gene: LRP8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.674

The method score is based on:

Property Details
Experiments 12950167, 8626535, 32814053
Identification Methods pull down, two hybrid array, two hybrid pooling approach, validated two hybrid, affinity technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0030425 - dendrite
and 2 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 317
Hs

1 963
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024