Interactor 1: APOE (P02649)
Apolipoprotein E (Apo-E)
Gene: APOE

Interactor 2: TREM2 (Q9NZC2)
Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)
Gene: TREM2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 27477018
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001540 - amyloid-beta binding
GO:0005543 - phospholipid binding
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0008289 - lipid binding
and 8 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 317
Hs

1 230
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024