Interactor 1: PNPH (P00491)
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
Gene: PNP
Interactor 2: PNPH (P00491)
Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase)
Gene: PNP
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.954 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 32296183, 39358380, 20212140, 25502805, 31515488, unassigned1304 |
| Identification Methods | two hybrid, cross-linking study, x-ray crystallography, two hybrid array, two hybrid prey pooling approach, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PNP_UDP_1~PNP_UDP_1 |
| Common GO terms | GO:0000255 - allantoin metabolic process GO:0001882 - nucleoside binding GO:0002060 - purine nucleobase binding GO:0004731 - purine-nucleoside phosphorylase activity GO:0005576 - extracellular region and 23 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
