HitPredict

Interactor 1: MBP (P02686)
Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein)
Gene: MBP

Interactor 2: MK14 (Q16539)
Mitogen-activated protein kinase 14 (MAP kinase 14) (MAPK 14) (EC 2.7.11.24) (Cytokine suppressive anti-inflammatory drug-binding protein) (CSAID-binding protein) (CSBP) (MAP kinase MXI2) (MAX-interacting protein 2) (Mitogen-activated protein kinase p38 alpha) (MAP kinase p38 alpha) (Stress-activated protein kinase 2a) (SAPK2a)
Gene: MAPK14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

Property	Details
Experiments	10978313, 10708586, 17906618, 12429732
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 304 Hs			1 360
+	Hs
		362072 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK12_HUMAN (1-351): 1.68e-146: 420: 62.99
+	Hs
		362089 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK11_HUMAN (1-348): 2.11e-145: 417: 75.58
+	Hs
		173805 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK13_HUMAN (4-360): 1.04e-142: 410: 59.78
+	Hs
		362059 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK03_HUMAN (11-354): 1.1e-141: 408: 47.86
+	Hs
		362061 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK01_HUMAN (10-350): 2.66e-138: 399: 47.70
+	Hs
		362066 MBP_HUMAN (1-304): 1.69e-179: 498: 100.00		MK08_HUMAN (2-348): 5.3e-108: 324: 47.11
+	Mm
		381388 MBP_MOUSE (1-240): 5.07e-132: 376: 85.06		MK03_MOUSE (14-350): 2.51e-143: 412: 48.55
+	Mm
		381380 MBP_MOUSE (1-240): 5.07e-132: 376: 85.06		MK01_MOUSE (10-350): 2e-138: 399: 47.70
+	Rn
		362114 MBP_RAT (134-304): 1.78e-87: 261: 81.82		MK01_RAT (10-350): 2e-138: 399: 47.70
+	Xl
		953599 MBP_XENLA (134-304): 1.25e-69: 215: 58.01		Q6DFK6_XENLA (2-350): 7.88e-142: 407: 46.91