HitPredict - High confidence protein-protein interactions

Interactor 1: APOH (P02749)
Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)
Gene: APOH

Interactor 2: APOH (P02749)
Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)
Gene: APOH

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	19805618, 18822289
Identification Methods	molecular sieving, surface plasmon resonance, saturation binding
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Sushi~Sushi, Sushi~Sushi_2, Sushi_2~Sushi_2
Common GO terms	GO:0001937 - negative regulation of endothelial cell proliferation GO:0002456 - T cell mediated immunity GO:0005543 - phospholipid binding GO:0005576 - extracellular region GO:0005615 - extracellular space and 25 others more... GO:0005886 - plasma membrane GO:0006641 - triglyceride metabolic process GO:0007597 - blood coagulation, intrinsic pathway GO:0008201 - heparin binding GO:0008289 - lipid binding GO:0009986 - cell surface GO:0010596 - negative regulation of endothelial cell migration GO:0016525 - negative regulation of angiogenesis GO:0030194 - positive regulation of blood coagulation GO:0030195 - negative regulation of blood coagulation GO:0031089 - platelet dense granule lumen GO:0031639 - plasminogen activation GO:0033033 - negative regulation of myeloid cell apoptotic process GO:0034197 - triglyceride transport GO:0034361 - very-low-density lipoprotein particle GO:0034364 - high-density lipoprotein particle GO:0034392 - negative regulation of smooth muscle cell apoptotic process GO:0042627 - chylomicron GO:0045959 - negative regulation of complement activation, classical pathway GO:0051006 - positive regulation of lipoprotein lipase activity GO:0051917 - regulation of fibrinolysis GO:0051918 - negative regulation of fibrinolysis GO:0060230 - lipoprotein lipase activator activity GO:0062023 - collagen-containing extracellular matrix GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	345
Hs

1	345

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Last updated: 15 Jul 2024