Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 25402006, 24658140, unassigned2173
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 140
+ Hs
+ Hs
+ Mm

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Last updated: 11Aug2025