Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 19738201
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~fn3, PK_Tyr_Ser-Thr~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0008284 - positive regulation of cell population proliferation
GO:0034446 - substrate adhesion-dependent cell spreading
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 452
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024