Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: SPCS2 (Q15005)
Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Gene: SPCS2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.55 | 0.551 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20029029, unassigned2173 |
| Identification Methods | protein complementation assay, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005789 - endoplasmic reticulum membrane |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
