Interactor 1: PLF4 (P02776)
Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)]
Gene: PF4

Interactor 2: PLF4 (P02776)
Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into: Platelet factor 4, short form (Endothelial cell growth inhibitor)]
Gene: PF4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 8031770, 7547867, 7835432, 19805618, 28381538
Identification Methods x-ray crystallography, pull down, molecular sieving, surface plasmon resonance
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0006954 - inflammatory response
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
and 25 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 101
Hs

1 101
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Last updated: 15 Jul 2024