Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 10531064, 34709727, 20208545, 29302006, 23384347
Identification Methods x-ray crystallography, affinity chromatography technology, proximity labelling technology, molecular sieving, cosedimentation in solution, comigration in gel electrophoresis
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PA~PA, PA~Peptidase_M28, PA~TFR_dimer, Peptidase_M28~Peptidase_M28, Peptidase_M28~TFR_dimer, TFR_dimer~TFR_dimer
Common GO terms GO:0001618 - virus receptor activity
GO:0001666 - response to hypoxia
GO:0001934 - positive regulation of protein phosphorylation
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
and 54 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 760
Hs

1 760
+ Hs
+ Zm
+ Hs

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Last updated: 15 Jul 2024