HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21182205
Identification Methods	affinity chromatography technology, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 595
+	Hs
		364384 TFR1_HUMAN (1-760): 0: 971: 100.00		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		320148 TFR1_HUMAN (1-760): 0: 971: 100.00		ERR2_HUMAN (92-547): 4.3e-116: 354: 34.86
+	Hs
		364126 TFR1_HUMAN (1-760): 0: 971: 100.00		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Hs
		369897 ERMP1_HUMAN (302-699): 8.48e-72: 253: 14.78		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		487354 FOLH1_HUMAN (116-752): 0: 643: 24.40		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		1187507 ERMP1_HUMAN (302-699): 8.48e-72: 253: 14.78		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88