HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0031410 - cytoplasmic vesicle GO:0035556 - intracellular signal transduction GO:0048471 - perinuclear region of cytoplasm and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 192
+	Hs
		364237 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		364158 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		364434 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		364244 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		364223 TFR1_HUMAN (1-760): 0: 971: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		364228 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		364142 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		364164 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49