HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle GO:0070062 - extracellular exosome and 1 others more... GO:1903561 - extracellular vesicle
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 2472
+	Hs
		164549 TFR1_HUMAN (1-760): 0: 971: 100.00		SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41
+	Hs
		364246 TFR1_HUMAN (1-760): 0: 971: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		364276 TFR1_HUMAN (1-760): 0: 971: 100.00		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		211455 TFR1_HUMAN (1-760): 0: 971: 100.00		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Dm
		54306 A1ZBK1_DROME (293-607): 9.22e-58: 213: 13.76		A1Z9J3_DROME (3-518): 3.22e-10: 68.2: 15.60