HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043066 - negative regulation of apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 855
+	Hs
		364255 TFR1_HUMAN (1-760): 0: 971: 100.00		DDR1_HUMAN (22-849): 0: 655: 52.08
+	Hs
		364152 TFR1_HUMAN (1-760): 0: 971: 100.00		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		364129 TFR1_HUMAN (1-760): 0: 971: 100.00		NTRK1_HUMAN (551-850): 5.06e-101: 333: 42.62
+	Hs
		364291 TFR1_HUMAN (1-760): 0: 971: 100.00		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		364141 TFR1_HUMAN (1-760): 0: 971: 100.00		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Rn
		544919 TFR1_RAT (1-760): 0: 939: 76.25		INSR_RAT (511-849): 4.34e-54: 206: 37.46
+	Rn
		70289 TFR2_RAT (54-760): 0: 723: 42.67		INSR_RAT (511-849): 4.34e-54: 206: 37.46