HitPredict

Interactor 1: TRFL (P02788)
Lactotransferrin (Lactoferrin) (EC 3.4.21.-) (Growth-inhibiting protein 12) (Talalactoferrin) [Cleaved into: Lactoferricin-H (Lfcin-H); Kaliocin-1; Lactoferroxin-A; Lactoferroxin-B; Lactoferroxin-C]
Gene: LTF

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	15588942, 12522000
Identification Methods	electrophoretic mobility supershift assay, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0045669 - positive regulation of osteoblast differentiation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 358
+	Mm
		435817 TRFL_MOUSE (1-710): 0: 994: 70.56		CEBPA_MOUSE (1-358): 4.3e-64: 209: 91.19
+	Hs
		364682 TRFL_HUMAN (1-710): 0: 1048: 100.00		CEBPE_HUMAN (36-358): 7.89e-34: 128: 36.92
+	Hs
		364659 TRFL_HUMAN (1-710): 0: 1048: 100.00		CEBPD_HUMAN (89-355): 4.07e-31: 120: 28.84
+	Mm
		435818 TRFL_MOUSE (1-710): 0: 994: 70.56		CEBPE_MOUSE (36-358): 4.44e-38: 139: 36.31