HitPredict

Interactor 1: FRIH (P02794)
Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed]
Gene: FTH1

Interactor 2: NCOA4 (Q13772)
Nuclear receptor coactivator 4 (NCoA-4) (Androgen receptor coactivator 70 kDa protein) (70 kDa AR-activator) (70 kDa androgen receptor coactivator) (Androgen receptor-associated protein of 70 kDa) (Ret-activating protein ELE1)
Gene: NCOA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	26436293, 28877469, 25327288, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006879 - intracellular iron ion homeostasis GO:0044754 - autolysosome
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 614
+	Hs
		364886 FRIL_HUMAN (5-179): 1.8e-74: 223: 55.43		NCOA4_HUMAN (1-614): 0: 1241: 100.00
+	Hs
		73203 FRIH_HUMAN (1-183): 9.05e-87: 254: 100.00		B4DZ85_HUMAN (167-614): 0: 909: 100.00