HitPredict

Interactor 1: HSP83 (P02828)
Heat shock protein 83 (HSP 82)
Gene: HSP83

Interactor 2: EGFR (P04412)
Epidermal growth factor receptor (Egfr) (EC 2.7.10.1) (Drosophila relative of ERBB) (Gurken receptor) (Protein torpedo)
Gene: EGFR

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22028469
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 717 Dm			1 1426
+	Hs
		438028 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHB1_HUMAN (518-1298): 1.35e-177: 557: 18.38
+	Hs
		438029 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHA4_HUMAN (518-1296): 9.08e-169: 533: 18.31
+	Hs
		438189 HS90B_HUMAN (7-717): 0: 1060: 78.48		ERBB4_HUMAN (415-1408): 2.11e-156: 509: 25.96
+	Hs
		437918 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHA2_HUMAN (531-1256): 4.15e-156: 499: 18.62
+	Hs
		437838 HS90B_HUMAN (7-717): 0: 1060: 78.48		FGFR1_HUMAN (763-1251): 9.7e-130: 423: 23.88
+	Hs
		437897 HS90B_HUMAN (7-717): 0: 1060: 78.48		FGFR3_HUMAN (765-1242): 5.84e-108: 363: 23.13
+	Hs
		437966 HS90B_HUMAN (7-717): 0: 1060: 78.48		ABL2_HUMAN (932-1293): 8.55e-105: 363: 35.36
+	Gg
		94460 HS90B_CHICK (3-717): 0: 1069: 77.37		KSYK_CHICK (914-1187): 1.15e-50: 192: 37.77
+	Hs
		337314 HS90B_HUMAN (7-717): 0: 1060: 78.48		ABL1_HUMAN (944-1194): 4.41e-51: 199: 42.52
+	Hs
		69196 HS90B_HUMAN (7-717): 0: 1060: 78.48		A9UEZ6_HUMAN (944-1194): 1.67e-50: 199: 42.52
+	Dm
		365472 HSP83_DROME (1-717): 0: 1066: 100.00		SRC42_DROME (944-1197): 1.14e-51: 192: 41.31
+	Dm
		365495 HSP83_DROME (1-717): 0: 1066: 100.00		ACK_DROME (910-1198): 1.29e-48: 191: 37.42
+	Hs
		437960 HS90B_HUMAN (7-717): 0: 1060: 78.48		CSK_HUMAN (937-1190): 7.09e-53: 194: 40.47
+	Hs
		438096 HS90B_HUMAN (7-717): 0: 1060: 78.48		FAK1_HUMAN (934-1196): 1.82e-48: 191: 37.87
+	Hs
		437967 HS90B_HUMAN (7-717): 0: 1060: 78.48		FRK_HUMAN (944-1190): 8.33e-50: 187: 38.65
+	Hs
		437855 HS90B_HUMAN (7-717): 0: 1060: 78.48		INSRR_HUMAN (402-712): 8.01e-33: 141: 20.43
+	Hs
		437893 HS90B_HUMAN (7-717): 0: 1060: 78.48		ERBB3_HUMAN (85-429): 2.48e-31: 136: 19.85
+	Hs
		337799 HS90B_HUMAN (7-717): 0: 1060: 78.48		EGFR_HUMAN (100-413): 3.59e-29: 129: 19.49
+	Hs
		383544 HS90B_HUMAN (7-717): 0: 1060: 78.48		ERBB2_HUMAN (111-415): 5.1e-23: 109: 21.02
+	Hs
		435497 HS90B_HUMAN (7-717): 0: 1060: 78.48		IGF1R_HUMAN (402-683): 2.59e-19: 97.1: 18.73