Interactor 1: HSP83 (P02828)
Heat shock protein 83 (HSP 82)
Gene: HSP83

Interactor 2: CDC37 (Q24276)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (Protein enhancer of sevenless 3B)
Gene: CDC37

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 30245208
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~HSP90, CDC37_N~HSP90
Common GO terms GO:0002052 - positive regulation of neuroblast proliferation
GO:0005158 - insulin receptor binding
GO:0005737 - cytoplasm
GO:0006457 - protein folding
GO:0046628 - positive regulation of insulin receptor signaling pathway
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 717
Dm

1 389
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Sc
+ Sc
+ Hs

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Last updated: 15 Jul 2024