HitPredict

Interactor 1: HSP83 (P02828)
Heat shock protein 83 (HSP 82)
Gene: HSP83

Interactor 2: JAK (Q24592)
Tyrosine-protein kinase hopscotch (EC 2.7.10.2)
Gene: hop

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	25822791
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 717 Dm			1 1177
+	Hs
		433218 HS90B_HUMAN (7-717): 0: 1060: 78.48		YES_HUMAN (731-1166): 5.28e-106: 346: 22.90
+	Dm
		365472 HSP83_DROME (1-717): 0: 1066: 100.00		SRC42_DROME (879-1166): 2.09e-103: 338: 30.95
+	Hs
		437847 HS90B_HUMAN (7-717): 0: 1060: 78.48		SRC_HUMAN (854-1166): 3.12e-105: 343: 28.48
+	Hs
		411949 HS90B_HUMAN (7-717): 0: 1060: 78.48		FYN_HUMAN (731-1166): 2.36e-104: 341: 23.87
+	Hs
		437966 HS90B_HUMAN (7-717): 0: 1060: 78.48		ABL2_HUMAN (864-1176): 3.14e-97: 338: 27.45
+	Hs
		437823 HS90B_HUMAN (7-717): 0: 1060: 78.48		FGR_HUMAN (777-1168): 4.45e-100: 329: 22.74
+	Hs
		437967 HS90B_HUMAN (7-717): 0: 1060: 78.48		FRK_HUMAN (880-1162): 3.49e-100: 329: 29.76
+	Hs
		337314 HS90B_HUMAN (7-717): 0: 1060: 78.48		ABL1_HUMAN (864-1159): 2.93e-94: 328: 29.67
+	Hs
		411556 HS90B_HUMAN (7-717): 0: 1060: 78.48		LCK_HUMAN (864-1164): 7.4e-100: 328: 28.62
+	Hs
		437817 HS90B_HUMAN (7-717): 0: 1060: 78.48		HCK_HUMAN (864-1164): 1.53e-97: 322: 28.29
+	Hs
		433526 HS90B_HUMAN (7-717): 0: 1060: 78.48		LYN_HUMAN (842-1152): 1.98e-92: 308: 28.25
+	Hs
		438007 HS90B_HUMAN (7-717): 0: 1060: 78.48		BLK_HUMAN (864-1152): 7.21e-91: 303: 30.03
+	Hs
		437918 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHA2_HUMAN (562-871): 4.78e-72: 262: 18.02
+	Hs
		438028 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHB1_HUMAN (583-871): 1.24e-71: 261: 18.57
+	Hs
		438029 HS90B_HUMAN (7-717): 0: 1060: 78.48		EPHA4_HUMAN (583-871): 7.01e-71: 258: 17.82
+	Hs
		438016 HS90B_HUMAN (7-717): 0: 1060: 78.48		JAK3_HUMAN (588-859): 2.61e-61: 231: 16.61
+	Hs
		238334 HS90B_HUMAN (7-717): 0: 1060: 78.48		JAK2_HUMAN (837-1169): 2.78e-42: 170: 20.58
+	Hs
		435497 HS90B_HUMAN (7-717): 0: 1060: 78.48		IGF1R_HUMAN (894-1155): 5.7e-42: 170: 34.78
+	Hs
		437906 HS90B_HUMAN (7-717): 0: 1060: 78.48		JAK1_HUMAN (826-1177): 3.77e-42: 170: 19.68
+	Hs
		437921 HS90B_HUMAN (7-717): 0: 1060: 78.48		TYK2_HUMAN (881-1174): 1e-37: 156: 22.09