HitPredict

Interactor 1: HSP83 (P02828)
Heat shock protein 83 (HSP 82)
Gene: HSP83

Interactor 2: Q9VPN5 (Q9VPN5)
Stress-induced-phosphoprotein 1
Gene: Stip1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	21186352, 25822791, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005737 - cytoplasm GO:0098866 - multivesicular body fusion to apical plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 717 Dm			1 490
+	Hs
		438533 HS90B_HUMAN (7-717): 0: 1060: 78.48		RPAP3_HUMAN (308-467): 3.75e-30: 126: 30.63
+	Hs
		437930 HS90B_HUMAN (7-717): 0: 1060: 78.48		STIP1_HUMAN (2-187): 5.3e-20: 95: 27.42
+	Hs
		438201 HS90B_HUMAN (7-717): 0: 1060: 78.48		TOM34_HUMAN (307-434): 6.68e-20: 92.1: 26.47
+	Hs
		431774 HS90A_HUMAN (3-717): 0: 1053: 78.13		SPAG1_HUMAN (2-196): 1.6e-20: 97.3: 18.69
+	Hs
		111934 K9JA46_HUMAN (3-717): 0: 1053: 78.13		STIP1_HUMAN (2-187): 5.3e-20: 95: 27.42
+	Hs
		431574 HS90A_HUMAN (3-717): 0: 1053: 78.13		STIP1_HUMAN (2-187): 5.3e-20: 95: 27.42
+	Mm
		513680 HS90B_MOUSE (7-717): 0: 1064: 78.48		PPP5_MOUSE (149-300): 9.14e-16: 81.7: 19.61
+	Hs
		431886 HS90A_HUMAN (3-717): 0: 1053: 78.13		TOM34_HUMAN (307-434): 6.68e-20: 92.1: 26.47
+	Hs
		174561 HS90B_HUMAN (7-717): 0: 1060: 78.48		OGT1_HUMAN (306-475): 1.67e-15: 81.5: 13.45
+	Hs
		174556 HS90A_HUMAN (3-717): 0: 1053: 78.13		OGT1_HUMAN (306-475): 1.67e-15: 81.5: 13.45
+	Hs
		213454 HS90B_HUMAN (7-717): 0: 1060: 78.48		SGTA_HUMAN (309-462): 1.21e-13: 73.6: 29.22
+	Hs
		297025 HS90B_HUMAN (7-717): 0: 1060: 78.48		TOM70_HUMAN (4-265): 9.65e-12: 69.2: 13.92
+	Hs
		213451 HS90A_HUMAN (3-717): 0: 1053: 78.13		SGTA_HUMAN (309-462): 1.21e-13: 73.6: 29.22
+	Hs
		438021 HS90B_HUMAN (7-717): 0: 1060: 78.48		PPP5_HUMAN (1-103): 3.93e-10: 63.9: 32.04
+	Hs
		297024 HS90A_HUMAN (3-717): 0: 1053: 78.13		TOM70_HUMAN (4-265): 9.65e-12: 69.2: 13.92
+	Hs
		438464 HS90B_HUMAN (7-717): 0: 1060: 78.48		DNJC7_HUMAN (7-106): 3.46e-09: 60.8: 33.00
+	Hs
		431797 HS90A_HUMAN (3-717): 0: 1053: 78.13		IFT88_HUMAN (3-172): 1.92e-10: 65.4: 10.59
+	Hs
		111935 K9JA46_HUMAN (3-717): 0: 1053: 78.13		PPP5_HUMAN (1-103): 3.93e-10: 63.9: 32.04
+	Hs
		431681 HS90A_HUMAN (3-717): 0: 1053: 78.13		PPP5_HUMAN (1-103): 3.93e-10: 63.9: 32.04
+	Hs
		432195 HS90A_HUMAN (3-717): 0: 1053: 78.13		DNJC7_HUMAN (7-106): 3.46e-09: 60.8: 33.00