HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 24462205, 26217697, 9819422, 11967834, 24435512, 26804907, 28363677, 25452130, 27615124, 17908693, 29557065, 9187656, 12667448, 32565117, 19906642, 19032597, 19696785, 16625188, 20736353, 23396352 and 3 others

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Identification Methods affinity chromatography technology, unspecified method, x-ray crystallography, pull down, fluorescent resonance energy transfer, molecular sieving, cross-linking study, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90
Common GO terms GO:0000492 - box C/D snoRNP assembly
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 19 others

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Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 709
Sc

1 709
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Ca
+ Ce
+ Sp
+ Dm

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Last updated: 15 Jul 2024