HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: TOM70 (P07213)
Mitochondrial import receptor subunit TOM70 (70 kDa mitochondrial outer membrane protein) (Translocase of outer membrane 70 kDa subunit)
Gene: TOM70

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	27412066, 35876647
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0006626 - protein targeting to mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Sc			1 617
+	Mm
		513680 HS90B_MOUSE (5-709): 0: 1029: 61.68		PPP5_MOUSE (85-267): 5.98e-40: 154: 22.87
+	Hs
		438021 HS90B_HUMAN (5-709): 0: 1026: 62.13		PPP5_HUMAN (86-204): 1.12e-38: 151: 32.23
+	Hs
		111935 K9JA46_HUMAN (4-709): 0: 1015: 60.83		PPP5_HUMAN (86-204): 1.12e-38: 151: 32.23
+	Hs
		431681 HS90A_HUMAN (4-709): 0: 1015: 60.83		PPP5_HUMAN (86-204): 1.12e-38: 151: 32.23
+	Mm
		432427 HS90A_MOUSE (4-709): 0: 1012: 60.72		PPP5_MOUSE (85-267): 5.98e-40: 154: 22.87
+	Hs
		297025 HS90B_HUMAN (5-709): 0: 1026: 62.13		TOM70_HUMAN (164-605): 1.05e-20: 98.3: 11.63
+	Hs
		174561 HS90B_HUMAN (5-709): 0: 1026: 62.13		OGT1_HUMAN (17-311): 4.88e-18: 90.6: 8.70
+	Hs
		437930 HS90B_HUMAN (5-709): 0: 1026: 62.13		STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09
+	At
		646594 HS901_ARATH (3-709): 0: 1001: 64.03		OE64C_ARATH (71-214): 7.24e-26: 114: 29.45
+	Hs
		297024 HS90A_HUMAN (4-709): 0: 1015: 60.83		TOM70_HUMAN (164-605): 1.05e-20: 98.3: 11.63
+	At
		137805 HS904_ARATH (3-709): 0: 994: 61.72		OE64C_ARATH (71-214): 7.24e-26: 114: 29.45
+	Hs
		174556 HS90A_HUMAN (4-709): 0: 1015: 60.83		OGT1_HUMAN (17-311): 4.88e-18: 90.6: 8.70
+	Hs
		431797 HS90A_HUMAN (4-709): 0: 1015: 60.83		IFT88_HUMAN (171-615): 4.79e-18: 90.6: 9.56
+	Hs
		111934 K9JA46_HUMAN (4-709): 0: 1015: 60.83		STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09
+	Hs
		431574 HS90A_HUMAN (4-709): 0: 1015: 60.83		STIP1_HUMAN (42-274): 3.32e-18: 90.2: 17.09
+	At
		878283 HS902_ARATH (3-709): 0: 989: 62.29		OE64C_ARATH (71-214): 7.24e-26: 114: 29.45
+	At
		878278 HS902_ARATH (3-709): 0: 989: 62.29		HSOP2_ARATH (22-235): 2.23e-21: 100: 18.14
+	Hs
		431774 HS90A_HUMAN (4-709): 0: 1015: 60.83		SPAG1_HUMAN (223-450): 6.01e-10: 64.4: 13.60
+	Dm
		365481 HSP83_DROME (3-709): 0: 1000: 59.72		Q9VPN5_DROME (400-513): 2.43e-10: 65: 17.54
+	Sc
		365721 HSP82_YEAST (1-709): 0: 984: 100.00		STI1_YEAST (40-401): 1.41e-12: 72.4: 13.71