HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: CYPH (P14832)
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Cyclophilin) (CPH) (Cyclosporin A-binding protein) (PPI-II) (Rotamase)
Gene: CPR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26217697, 25452130, 31399574
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006457 - protein folding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 162
+	Hs
		438106 HS90B_HUMAN (5-709): 0: 1026: 62.13		PPID_HUMAN (2-162): 9.39e-87: 260: 58.58
+	Hs
		438624 HS90B_HUMAN (5-709): 0: 1026: 62.13		PPIE_HUMAN (2-161): 1.94e-87: 259: 61.25
+	Hs
		431781 HS90A_HUMAN (4-709): 0: 1015: 60.83		PPID_HUMAN (2-162): 9.39e-87: 260: 58.58
+	Hs
		432365 HS90A_HUMAN (4-709): 0: 1015: 60.83		PPIE_HUMAN (2-161): 1.94e-87: 259: 61.25
+	At
		646590 HS901_ARATH (3-709): 0: 1001: 64.03		CYP40_ARATH (2-162): 9.4e-85: 254: 52.94
+	At
		878280 HS902_ARATH (3-709): 0: 989: 62.29		CYP40_ARATH (2-162): 9.4e-85: 254: 52.94
+	Sc
		365886 HSP82_YEAST (1-709): 0: 984: 100.00		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Sc
		543295 HSC82_YEAST (1-709): 0: 973: 94.64		CYPC_YEAST (3-162): 2.46e-88: 257: 71.25
+	Sc
		540519 HSC82_YEAST (1-709): 0: 973: 94.64		CYPH_YEAST (1-162): 2.94e-88: 256: 100.00
+	Ca
		804532 HSP90_CANAL (4-709): 0: 959: 81.75		PPID_CANAL (2-162): 1.26e-64: 203: 61.14
+	Hs
		538104 ENPL_HUMAN (3-684): 0: 904: 45.97		PPIB_HUMAN (3-162): 9.69e-87: 254: 60.25