HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 9632755, 24488121, 31399574, 19536198, 16554755, 37968396, unassigned1933
Identification Methods affinity chromatography technology, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90
Common GO terms GO:0000492 - box C/D snoRNP assembly
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 11 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 709
Sc

1 705
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ At
+ Sc
+ Sc
+ Hs
+ Ca
+ Hs
+ Ce
+ Sp
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024