HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	31399574, 33326013, 37845327, 15879519
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006457 - protein folding GO:0051082 - unfolded protein binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 352
+	Hs
		431571 HS90A_HUMAN (4-709): 0: 1015: 60.83		DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93
+	Hs
		243260 HS90A_HUMAN (4-709): 0: 1015: 60.83		DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09
+	Sc
		365867 HSP82_YEAST (1-709): 0: 984: 100.00		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		543273 HSC82_YEAST (1-709): 0: 973: 94.64		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		543250 HSC82_YEAST (1-709): 0: 973: 94.64		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Dm
		1361622 Q9VAY2_DROME (3-680): 0: 837: 46.67		Q9VFV9_DROME (1-352): 8.97e-112: 332: 28.25