HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	15766533, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 923
+	Hs
		152851 HS90A_HUMAN (4-709): 0: 1015: 60.83		APAF_HUMAN (451-834): 2.56e-50: 195: 12.87
+	Sc
		366669 HSP82_YEAST (1-709): 0: 984: 100.00		COPA_YEAST (1-447): 1.7e-49: 192: 12.05
+	Hs
		438048 HS90B_HUMAN (5-709): 0: 1026: 62.13		WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95
+	Hs
		437971 HS90B_HUMAN (5-709): 0: 1026: 62.13		LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06
+	Hs
		431630 HS90A_HUMAN (4-709): 0: 1015: 60.83		LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06
+	Hs
		152853 ENPL_HUMAN (3-684): 0: 904: 45.97		APAF_HUMAN (451-834): 2.56e-50: 195: 12.87
+	Hs
		438057 HS90B_HUMAN (5-709): 0: 1026: 62.13		GBB2_HUMAN (342-550): 1.77e-09: 62.4: 21.46
+	Hs
		538184 ENPL_HUMAN (3-684): 0: 904: 45.97		WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95
+	Hs
		538141 ENPL_HUMAN (3-684): 0: 904: 45.97		LIS1_HUMAN (564-720): 5.47e-17: 86.5: 10.06