HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: MSP1 (P28737)
Outer mitochondrial transmembrane helix translocase (EC 7.4.2.-) (Mitochondrial sorting of proteins) (Tat-binding homolog 4)
Gene: MSP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	35876647
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0006626 - protein targeting to mitochondrion GO:0016887 - ATP hydrolysis activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 362
+	Rn
		709240 HS90B_RAT (5-709): 0: 1029: 61.68		KTNA1_RAT (31-361): 3.58e-96: 296: 30.26
+	Rn
		948939 HS90A_RAT (4-709): 0: 1014: 60.72		KTNA1_RAT (31-361): 3.58e-96: 296: 30.26
+	Hs
		265388 HS90A_HUMAN (4-709): 0: 1015: 60.83		KTNA1_HUMAN (17-361): 2.62e-94: 291: 30.11
+	Sc
		366752 HSP82_YEAST (1-709): 0: 984: 100.00		PRS8_YEAST (5-333): 9.57e-105: 315: 27.81
+	Mm
		513673 HS90B_MOUSE (5-709): 0: 1029: 61.68		TERA_MOUSE (72-362): 7.75e-83: 269: 32.77
+	Hs
		438031 HS90B_HUMAN (5-709): 0: 1026: 62.13		TERA_HUMAN (72-362): 7.75e-83: 269: 32.77
+	Sc
		543327 HSC82_YEAST (1-709): 0: 973: 94.64		MSP1_YEAST (1-362): 8.22e-107: 319: 100.00
+	Sc
		544264 HSC82_YEAST (1-709): 0: 973: 94.64		PRS8_YEAST (5-333): 9.57e-105: 315: 27.81
+	Hs
		431695 HS90A_HUMAN (4-709): 0: 1015: 60.83		TERA_HUMAN (72-362): 7.75e-83: 269: 32.77
+	Dm
		1181188 Q9VAY2_DROME (3-680): 0: 837: 46.67		TERA_DROME (73-362): 1e-81: 267: 31.85