HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 1084
+	Hs
		162346 HS90B_HUMAN (5-709): 0: 1026: 62.13		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Hs
		162341 HS90A_HUMAN (4-709): 0: 1015: 60.83		XPO1_HUMAN (3-1084): 0: 854: 46.40
+	Sc
		543345 HSC82_YEAST (1-709): 0: 973: 94.64		XPO1_YEAST (1-1084): 0: 833: 100.00
+	Ca
		804502 HSP90_CANAL (4-709): 0: 959: 81.75		XPOT_CANAL (25-1040): 6.8e-84: 296: 12.79
+	Sc
		367155 HSP82_YEAST (1-709): 0: 984: 100.00		MTR10_YEAST (25-890): 2.39e-75: 270: 14.40
+	Sc
		366600 HSP82_YEAST (1-709): 0: 984: 100.00		MSN5_YEAST (25-223): 1.76e-10: 67.5: 17.01
+	Sc
		543478 HSC82_YEAST (1-709): 0: 973: 94.64		XPOT_YEAST (13-523): 8.56e-11: 68.3: 14.31