HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: CBS (P32582)
Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) (Sulfur transfer protein 4)
Gene: CYS4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	24488121, 31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 507
+	Hs
		437943 HS90B_HUMAN (5-709): 0: 1026: 62.13		CBS_HUMAN (2-507): 0: 543: 40.77
+	Sc
		543408 HSC82_YEAST (1-709): 0: 973: 94.64		CBS_YEAST (1-507): 0: 565: 100.00
+	Ca
		804487 HSP90_CANAL (4-709): 0: 959: 81.75		Q59T95_CANAL (1-506): 4.07e-164: 475: 56.75
+	Sc
		343056 HSP82_YEAST (1-709): 0: 984: 100.00		THDH_YEAST (2-361): 1.54e-78: 258: 16.26
+	Zm
		8746 A0A1D6ES19_MAIZE (3-709): 0: 984: 63.42		A0A1D6GJ69_MAIZE (4-361): 7.73e-75: 249: 20.00
+	Sc
		343082 HSC82_YEAST (1-709): 0: 973: 94.64		THDH_YEAST (2-361): 1.54e-78: 258: 16.26
+	Sc
		543529 HSC82_YEAST (1-709): 0: 973: 94.64		LTHAD_YEAST (5-326): 3.1e-66: 218: 20.48
+	Sc
		365857 HSP82_YEAST (1-709): 0: 984: 100.00		STDH_YEAST (20-323): 1.86e-14: 76.7: 17.85
+	Sc
		543269 HSC82_YEAST (1-709): 0: 973: 94.64		STDH_YEAST (20-323): 1.86e-14: 76.7: 17.85