HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RFC3 (P38629)
Replication factor C subunit 3 (Replication factor C3) (Activator 1 40 kDa subunit)
Gene: RFC3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 340
+	Sc
		543665 HSC82_YEAST (1-709): 0: 973: 94.64		RFC3_YEAST (1-340): 2.34e-95: 288: 100.00
+	Sc
		366387 HSP82_YEAST (1-709): 0: 984: 100.00		RFC2_YEAST (1-329): 5.33e-75: 236: 32.26
+	Sc
		366383 HSP82_YEAST (1-709): 0: 984: 100.00		RFC4_YEAST (12-333): 2.2e-72: 229: 34.06
+	Sc
		543852 HSC82_YEAST (1-709): 0: 973: 94.64		RFC2_YEAST (1-329): 5.33e-75: 236: 32.26
+	Sc
		543847 HSC82_YEAST (1-709): 0: 973: 94.64		RFC4_YEAST (12-333): 2.2e-72: 229: 34.06
+	Sc
		543631 HSC82_YEAST (1-709): 0: 973: 94.64		RFC5_YEAST (14-332): 9.6e-71: 225: 21.97