HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: TOM71 (P38825)
Protein TOM71 (71 kDa mitochondrial outer membrane protein)
Gene: TOM71

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	19581297
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0006626 - protein targeting to mitochondrion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Sc			1 639
+	Sc
		365568 HSP82_YEAST (1-709): 0: 984: 100.00		TOM70_YEAST (6-639): 1.44e-70: 241: 47.99
+	Sc
		422983 HSC82_YEAST (1-709): 0: 973: 94.64		TOM70_YEAST (6-639): 1.44e-70: 241: 47.99
+	Hs
		431797 HS90A_HUMAN (4-709): 0: 1015: 60.83		IFT88_HUMAN (3-635): 2.63e-53: 197: 11.80
+	Hs
		438021 HS90B_HUMAN (5-709): 0: 1026: 62.13		PPP5_HUMAN (109-385): 3.62e-35: 141: 20.00
+	Mm
		513680 HS90B_MOUSE (5-709): 0: 1029: 61.68		PPP5_MOUSE (109-234): 5.8e-34: 137: 28.79
+	Hs
		111935 K9JA46_HUMAN (4-709): 0: 1015: 60.83		PPP5_HUMAN (109-385): 3.62e-35: 141: 20.00
+	Hs
		431681 HS90A_HUMAN (4-709): 0: 1015: 60.83		PPP5_HUMAN (109-385): 3.62e-35: 141: 20.00
+	Mm
		432427 HS90A_MOUSE (4-709): 0: 1012: 60.72		PPP5_MOUSE (109-234): 5.8e-34: 137: 28.79
+	Hs
		297025 HS90B_HUMAN (5-709): 0: 1026: 62.13		TOM70_HUMAN (193-627): 4.12e-24: 109: 12.96
+	Hs
		174561 HS90B_HUMAN (5-709): 0: 1026: 62.13		OGT1_HUMAN (37-352): 9.89e-21: 99.4: 11.71
+	Hs
		297024 HS90A_HUMAN (4-709): 0: 1015: 60.83		TOM70_HUMAN (193-627): 4.12e-24: 109: 12.96
+	Hs
		174556 HS90A_HUMAN (4-709): 0: 1015: 60.83		OGT1_HUMAN (37-352): 9.89e-21: 99.4: 11.71
+	Hs
		431774 HS90A_HUMAN (4-709): 0: 1015: 60.83		SPAG1_HUMAN (217-467): 8.85e-15: 80.1: 11.16
+	Hs
		437930 HS90B_HUMAN (5-709): 0: 1026: 62.13		STIP1_HUMAN (49-300): 4.81e-09: 61.2: 9.47
+	Dm
		365481 HSP83_DROME (3-709): 0: 1000: 59.72		Q9VPN5_DROME (115-414): 1.97e-15: 81.2: 14.98
+	Hs
		111934 K9JA46_HUMAN (4-709): 0: 1015: 60.83		STIP1_HUMAN (49-300): 4.81e-09: 61.2: 9.47
+	Hs
		431574 HS90A_HUMAN (4-709): 0: 1015: 60.83		STIP1_HUMAN (49-300): 4.81e-09: 61.2: 9.47
+	Sc
		365721 HSP82_YEAST (1-709): 0: 984: 100.00		STI1_YEAST (62-371): 1.86e-14: 78.5: 15.14
+	At
		878278 HS902_ARATH (3-709): 0: 989: 62.29		HSOP2_ARATH (377-489): 9e-13: 73.2: 15.93
+	Sc
		543117 HSC82_YEAST (1-709): 0: 973: 94.64		STI1_YEAST (62-371): 1.86e-14: 78.5: 15.14