HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: RSP5 (P39940)
E3 ubiquitin-protein ligase RSP5 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase RSP5) (Reverses SPT-phenotype protein 5)
Gene: RSP5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26217697, 26804907, 25452130
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 809
+	Sc
		543785 HSC82_YEAST (1-709): 0: 973: 94.64		RSP5_YEAST (1-809): 0: 825: 100.00
+	Hs
		438516 HS90B_HUMAN (5-709): 0: 1026: 62.13		WWP1_HUMAN (108-809): 0: 690: 40.33
+	Hs
		125101 HS90B_HUMAN (5-709): 0: 1026: 62.13		WWP2_HUMAN (100-809): 0: 684: 40.81
+	Hs
		432252 HS90A_HUMAN (4-709): 0: 1015: 60.83		WWP1_HUMAN (108-809): 0: 690: 40.33
+	Hs
		125097 HS90A_HUMAN (4-709): 0: 1015: 60.83		WWP2_HUMAN (100-809): 0: 684: 40.81
+	Hs
		538146 ENPL_HUMAN (3-684): 0: 904: 45.97		NEDD4_HUMAN (102-807): 0: 668: 39.67
+	Hs
		438309 HS90B_HUMAN (5-709): 0: 1026: 62.13		HUWE1_HUMAN (252-808): 3.56e-167: 539: 31.78
+	Hs
		432005 HS90A_HUMAN (4-709): 0: 1015: 60.83		HUWE1_HUMAN (252-808): 3.56e-167: 539: 31.78
+	Sc
		366793 HSP82_YEAST (1-709): 0: 984: 100.00		TOM1_YEAST (370-808): 5.87e-157: 509: 37.36
+	Sc
		544310 HSC82_YEAST (1-709): 0: 973: 94.64		TOM1_YEAST (370-808): 5.87e-157: 509: 37.36
+	Hs
		538295 ENPL_HUMAN (3-684): 0: 904: 45.97		HUWE1_HUMAN (252-808): 3.56e-167: 539: 31.78
+	Zm
		17433 A0A1D6GWE1_MAIZE (2-678): 0: 548: 48.94		A0A1D6MU59_MAIZE (364-807): 4.08e-160: 518: 37.20