HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: COPA (P53622)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (Retrieval from endoplasmic reticulum protein 1) (Secretory protein 22) (Suppressor of osmo-sensitivity 1)
Gene: COP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	11805837, 31399574
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 1201
+	Hs
		438048 HS90B_HUMAN (5-709): 0: 1026: 62.13		WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50
+	Hs
		437971 HS90B_HUMAN (5-709): 0: 1026: 62.13		LIS1_HUMAN (242-518): 1.05e-41: 160: 13.84
+	Sc
		366452 HSP82_YEAST (1-709): 0: 984: 100.00		COPB2_YEAST (131-923): 2.71e-52: 201: 9.21
+	Hs
		431630 HS90A_HUMAN (4-709): 0: 1015: 60.83		LIS1_HUMAN (242-518): 1.05e-41: 160: 13.84
+	Sc
		543926 HSC82_YEAST (1-709): 0: 973: 94.64		COPB2_YEAST (131-923): 2.71e-52: 201: 9.21
+	Hs
		152851 HS90A_HUMAN (4-709): 0: 1015: 60.83		APAF_HUMAN (484-666): 6.4e-21: 101: 12.37
+	Hs
		538184 ENPL_HUMAN (3-684): 0: 904: 45.97		WDR5_HUMAN (408-680): 1.68e-50: 184: 8.50
+	Hs
		538141 ENPL_HUMAN (3-684): 0: 904: 45.97		LIS1_HUMAN (242-518): 1.05e-41: 160: 13.84
+	Hs
		152853 ENPL_HUMAN (3-684): 0: 904: 45.97		APAF_HUMAN (484-666): 6.4e-21: 101: 12.37